Best Non-Toxic Body Oil in 2024
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Find Non-Toxic Body Oil
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Organic Sweet Almond Oil for Body - Sky Organics
Product Details
- Rich in vitamins A and E, which deliver long-lasting moisture and softness to the skin.
- Features a silky, lightweight texture that absorbs easily into the skin without leaving a greasy residue.
- Retrieved through cold-pressing to retain vitamins and antioxidants, and to eliminate potential irritants.
- Can be used as a skin-soothing massage oil, daily body oil, carrier oil for essential oils, or in DIY beauty recipes.
- USDA certified organic, 100% vegan, and cruelty-free.
- Responsibly made in small batches with high-quality ingredients.
Pros & Cons
Pros Mentioned
- Moisturizing
- Non-greasy
- Healing
Cons Mentioned
- Inconsistent
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Prunus Amygdalus Dulcis (Almond) Oil*
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User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Sweet Almond Skin Care Oil - Aura Cacia
Product Details
- Non-GMO Project Verified sweet almond oil suitable for everyday, head-to-toe skin care.
- Fast-absorbing and ideal as a carrier oil for diluting essential oils.
- Contains non-GMO Vitamin E to preserve freshness.
- Can be used for facial care, body care, and hair care.
- Product authenticity and quality assured through rigorous testing and long-standing supplier relationships.
- Supports the Positive Change Project, a grant program aiding organizations that help women transform their lives.
- Part of Frontier Co-op, a member-owned cooperative focused on responsible business practices.
Pros & Cons
Pros Mentioned
- Hydrating
- Softening
- Natural
Cons Mentioned
- Leaking
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Organic Prunus Amygdalus Dulcis (Sweet Almond) Oil, Mixed Tocopherol (Vitamin E, Helianthus Annuus (Sunflower) Oil)
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User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Fresh Body Oil - Qet Botanicals
Pros & Cons
Pros Mentioned
- None
Cons Mentioned
- Smelly
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Vitis Vinifera (Grape) Seed Oil*, Olea Europaea (Olive) Fruit Oil*, Helianthus Annus (Sunflower) Seed Oil*, Brassica Oleracea (Broccoli) Seed Oil, Tocopherol (Non-GMO Vitamin E), Lavandula Angustifolia (Lavender) Flower Oil*, Mentha Piperita (Peppermint) Leaf Oil*, Rubus Idaeus (Red Raspberry) Seed Oil, Rosmarinus Officinalis (Rosemary) Flower Oil*, Jasminum Sambac (Jasmine) Flower Oil* Organic Ingredient
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User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Undaria Algae Body Oil - Osea
Product Details
- Skin Revitalization: Lightweight, non-greasy body oil enriched with Undaria Algae for nourishing and skin-firming benefits.
- Luxurious Post-Shower Care: Scented, vegan body oil that leaves skin soft and smooth.
- Made in the USA: Crafted with synthetic-free plant-based ingredients, cruelty-free, and climate-neutral.
- Contains natural variations: Color variation is normal due to artisanal production; naturally occurring seaweed sediment may be present.
- Elevate self-care gifting: Includes eco-friendly spa and beauty gift sets that are vegan, cruelty-free, and devoid of harmful chemicals.
- Certifications: Holds Climate Neutral & Ocean Positive Certification.
- Pro Pump Tip: Instructions for unlocking and priming the pump for initial use.
Pros & Cons
Pros Mentioned
- Hydrating
- Softening
- Lightly-scented
Cons Mentioned
- Pricy
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Helianthus Annuus (Sunflower) Seed Oil, Undaria Pinnatifida Extract, Euterpe Oleracea (Acai) Pulp Oil, Linum Usitatissimum (Linseed) Seed Oil, Orbignya Oleifera (Babassu) Seed Oil, Oryza Sativa (Rice Bran) Oil, Passiflora Edulis (Passion Fruit) Seed Oil, Sesamum Indicum (Sesame) Seed Oil, Tocopherol, Citrus Aurantifolia (Lime) Oil, Citrus Paradisi (Grapefruit) Peel Oil, Cupressus Sempervirens (Cypress) Oil
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Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Organic Pure Radiance Body Oil - True Botanicals
Product Details
- Delivers nourishing moisture leaving skin feeling silky and sensually soft without feeling greasy.
- Formulated with a blend of hemp seed and sandalwood oils to replenish skin with ceramides and omega fatty acids.
- Hypoallergenic, suitable for sensitive skin types.
- Described as a pure oil blend without waxes or creams, allowing for better absorption into the skin.
- Provides a dose of antioxidants and essential fatty acids for smoother skin.
- Contains green tea seed, hemp seed, and sandalwood oils to help maintain a radiant glow while moisturizing and soothing the skin.
- Features a natural fragrance with notes of sandalwood.
- Non-toxic, cruelty-free, organic, wild-harvested, sustainable, non-GMO, and certified by MADESAFE.
Pros & Cons
Pros Mentioned
- Moisturizing
- Smell
- Non-greasy
Cons Mentioned
- Expensive
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Camellia Oleifera (Green Tea) Seed Oil*, Helianthus Annuus (Sunflower) Seed Oil*, Hemp Seed Oil*, Salvia Hispanica (Chia) Seed Oil*, Rosmarinus Officinalis (Rosemary) Leaf Extract*, Amyris Balsamifera Bark Oil, Bulnesia Sarmientoi Wood Oil, Cinnamomum Zeylanicum Leaf Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Juniperus Mexicana (Cedarwood) Oil, Pogostemon Cablin Oil, Santalum Austrocaledonicum (Sandalwood) Wood Oil, Citral, Eugenol, Limonene, Linalool *Denotes Organic Ingredient
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Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Noni Glow Body Oil - Kora Organics
Product Details
- Provides deep hydration and radiance to the skin
- Designed for individuals with dry skin to lock in moisture and enhance glow
- Contains organic Noni Extract, Rosehip, and Sunflower Seed Oils, which offer antioxidants and essential fatty acids
- Recommended usage: warm several drops in hands and apply all over the body until absorbed, use after lotion for best results
- Product formulation is certified organic, cruelty-free, and vegan
- Free from artificial fragrances and colors
Pros & Cons
Pros Mentioned
- Hydrating
- Nourishing
- Absorbent
Cons Mentioned
- Overpriced
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Rosa Canina (Rosehip) Seed Oil*, Dicaprylyl Carbonate, Helianthus Annuus (Sunflower) Seed Oil*, Hippophae Rhamnoides (Sea Buckthorn) Seed Oil*, Tocopherol*, Pelargonium Graveolens (Rose Geranium) Flower Oil, Morinda Citrifolia (Noni) Fruit Extract*, Glycine Soja (Soybean) Oil*, Rosa Damascena (Rose) Flower Oil*, Punica Granatum (Pomegranate) Seed Oil*, Citronellol**, Geraniol**, Linalool**, Citral**, Limonene**
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Body Oil - Clary Collection
Product Details
- Non-greasy oil that moisturizes the body without leaving a greasy residue, suitable for use as a lotion or massage oil.
- Can be used as daily moisturizer, shaving oil, adding to bathwater, or as a nourishing after-bath treatment.
- Features detoxifying qualities with benefits for skin, joints, inflammation, and irritations.
- Contains natural ingredients such as Calendula, Chamomile, Lavender, and Plantain, infused and bottled in small batches.
- Certified non-toxic by MADE SAFE®, ensuring it is free from harmful toxins.
- All-natural, organic, and non-GMO with sustainably sourced ingredients, cruelty-free and free from sulfates, phthalates, parabens, alcohol, and synthetic or artificial additives.
- Sourced from local herb farmers and beekeepers who follow organic and regenerative practices, and ethical harvesting.
Pros & Cons
Pros Mentioned
- Great
- Favorite
- Useful
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Organic Olive Oil, Organic Plantain Leaves, Organic Calendula Flowers, Organic Chamomile Flowers, Organic Lavender Flowers, Organic Rosemary Extract
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Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Coconut Body Oil - Annmarie
Product Details
- Nourishes and softens skin with a blend of oils infused with milk thistle, life everlasting, and calendula.
- Contains coconut oil, which is rich in lauric acid.
- Features a soothing lavender aroma.
- Can be used daily as an all-over body moisturizer after shower or bath.
- Functions as a massage oil when warmed between palms before application.
- May solidify at temperatures below 76°; can be liquified by running the bottle under hot water and shaking well.
Pros & Cons
Pros Mentioned
- Smoothing
- Soothing
- Moisturizing
Cons Mentioned
- Greasy
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Cocos Nucifera (Extra Virgin Coconut) Oil, Helianthus Annuus (Sunflower) Seed Oil, Herb-Infused Oil [Vitis Vinifera (Grape) Seed Oil, Calendula Officinalis (Calendula) Flower Extract, Symphytum Officinale (Comfrey) Leaf Extract, Symphytum Officinale (Comfrey) Root Extract, Echinacea Purpurea (Echinacea) Extract, Ginkgo Biloba (Gingko) Leaf Extract, Lycium Chinense (Goji Berry) Fruit Extract, Centella Asiatica (Gotu Kola) Leaf Extract, Hibiscus Sabdariffa (Hibiscus) Flower Extract, Lavandula Angustifolia (Lavender) Flower Extract, Melissa Officinalis (Lemon Balm) Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Helichrysum Arenarium (Life Everlasting) Flower Extract, Nelumbo Nucifera (Lotus) Stamen Extract, Plantago Lanceolata (Plantain) Leaf Extract, Rhodiola Rosea (Rhodiola) Root Extract, Aspalathus Linearis (Rooibos) Leaf Extract, Rosa Centifolia (Rose) Flower Extract, Althaea Officinalis (Marshmallow), Stellaria Media (Chickweed), Camellia Sinensis (Gunpowder Green Tea) Leaf Extract, Equisetum Arvense (Horsetail) Leaf Extract, Viola Tricolor (Violet) Extract, Euterpe Oleracea (Acai) Fruit Extract, Emblica Officinalis (Amla) Fruit Extract, Withania Somnifera (Ashwagandha) Root Extract, Boswellia Serrata (Sacred Frankincense) Resin Extract, Silybum Marianum (Milk Thistle) Seed Extract], Aloe Vera Oil [Caprylic/Capric Triglyceride (Fractionated Coconut Oil), Cocos Nucifera (Coconut) Oil, Aloe Barbadensis (Aloe Vera) Leaf Extract], Olea Europaea (Olive) Fruit Oil, Tocopherol (Non-Gmo Vitamin E), Lavandula Angustifolia (Lavender) Oil, Canarium Commune (Elemi) Oil, Myroxylon Balsamum (Peru Balsam) Oil, Boswellia Carterii (Frankincense) Gum Extract
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Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Daily Hydration Body Oil - SheaMoisture
Product Details
- Designed to moisturize dry skin, leaving it soft and pampered.
- Leaves skin with a natural glow without appearing greasy.
- Infused with exotic Acacia Senegal, Virgin Coconut Oil, Coconut Milk, and other oils for a hydrating, lightweight, and fast-absorbing formula.
- Suitable for everyday hydration across all skin types, including those that need minimal moisture.
- Can be used in various ways: as a bath oil, shower oil, after-shower body oil, or body moisturizer.
- Free from parabens, phthalates, mineral oil, and sulfates.
- Never tested on animals and has been tested for generations within the family.
- Part of a brand legacy started by Sofi Tucker in 1912, honoring her by continuing to use handcrafted Raw Shea Butter from women in Africa.
- Purchases support the brand's mission to reinvest back into their communities.
Pros & Cons
Pros Mentioned
- Moisturizing
- Non-greasy
- Fragrant
Cons Mentioned
- Expensive
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Helianthus Annuus (Sunflower) Seed Oil, Prunus Armeniaca (Apricot) Kernel Oil, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Fragrance, Olea Europaea (Olive) Fruit Oil, Tocopheryl Acetate, Butyrospermum Parkii (Shea) Butter, Cocos Nucifera (Coconut) Oil, Acacia Senegal Gum, Cocos Nucifera (Coconut) Fruit Juice, Cocos Nucifera (Coconut) Fruit Extract, Water, Glycerin (Vegetable)
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Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Dry Body Oil - Attitude
Product Details
- Enriched with jojoba and argan oils, rich in fatty acids; avocado oil, rich in vitamins; sunflower oil, rich in vitamin E; and grape seed oil, rich in polyphenols.
- Infused with a sandalwood scent featuring woody notes and a floral touch.
- Comes in a biodegradable cardboard package with a built-in push-up design.
- EWG Verified: Does not contain ingredients of concern according to EWG standards.
- PETA certified as vegan and cruelty-free.
- Features bamboo powder for exfoliating dead skin cells.
- Contains shea butter, Indian cress, and watercress to revitalize, repair, and soothe dry skin.
Pros & Cons
Pros Mentioned
- Absorbs
- Moisturizing
- Non-greasy
Cons Mentioned
- Packaging
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Helianthus Annuus (Sunflower) Seed Oil, Isopropyl Palmitate, Isostearyl Isostearate, Helianthus Annuus (Sunflower) Seed Wax, Octyldodecanol, Octyldodecyl Myristate, Argania Spinosa Kernel Oil, Moringa Oleifera Seed Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Vitis Vinifera (Grape) Seed Oil, Persea Gratissima (Avocado) Oil, Caprylic/Capric Triglyceride, Nasturtium Officinale (Watercress) Extract, Tropaeolum Majus (Indian Cress) Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Disclosed Fragrance, Components: Triethyl Citrate, Dihydrofarnesol, Beta-Ionone, Amyris Balsamifera Bark Oil, Juniperus Virginiana Oil
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User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Organic Everybody Loves The Sunshine Body Oil - Living Libations
Product Details
- Formulated as an after-sun body oil with a rich organic formula containing essential oils.
- Designed to extend a golden tan while preventing sun damage using organic turmeric and ginger.
- Promotes healthy Vitamin D absorption from the sun and limits free radical damage, although it is not an SPF substitute.
- Incorporates plant-based ingredients that help prevent burns and prolong the life of your tan.
- Made with natural, organic, and wildcrafted ingredients, handmade in small batches.
- Product variations in color, consistency, and scent are normal for natural products.
- Bottled in recyclable glass, ensuring environmental responsibility.
- Free from parabens, sulfates, cruelty, gluten, and entirely vegan.
Pros & Cons
Pros Mentioned
- Effective
- Natural
- Nourishing
Cons Mentioned
- Oily
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Desert Jojoba Plant, Virgin Coco-Creme, Red Raspberry Seed Oil, Seabuckthorn Berry Oil, Tamanu Berry, Essential Oils Of Schizandra Berry, Immortelle, Carrot Seed, Rose Otto, Cape-Chamomile, Frankincense, Sandalwood, Ginger, Lavender, Turmeric, Calendula, Palmarosa
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all personal care and cosmetic products on Welpr.
Anti-Aging Jasmine Body Oil - KOA LIFE
Product Details
- Formulated with nourishing plant-derived ingredients suitable for all skin types.
- Utilizes the medicinal power of plants to deeply moisturize and enhance skin radiance.
- Targets even skin tone, reduces signs of aging, and promotes a glowing, radiant complexion.
- Free from sulfates, parabens, and is cruelty-free.
- Developed by a socially conscious brand, created by women for women.
- Offers a satisfaction guarantee with customer support for dissatisfied users.
Pros & Cons
Pros Mentioned
- Moisturizing
- Absorbent
- Fragrant
Cons Mentioned
- Pricey
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use INCIDecoder.
Ingredients: Sweet Almond Oil, Grape Seed Oil, Rice Bran Oil, Cannabis Sativa (Hemp) Seed Oil, Jojoba Seed Oil, Olive Fruit Oil, Astragalus Membranous Root Extract, Glycyrrhiza Glabra Root Extract, Shitake Extract
Common Harmful Chemicals in Body Oil
Chemical Name
Why it’s harmful
Linalool is a naturally occurring terpene alcohol found in many flowers and spice plants, consisting of two enantiomers. It is widely used in commercial products for its pleasant floral and spicy scent, serving as a key ingredient in soaps, fragrances, food flavors, household products, and insecticides. In plants, linalool functions as a metabolite, volatile oil component, antimicrobial agent, and aroma compound. Acute exposure to linalool can lead to central depressive effects with symptoms such as ataxia, reduced motor activity, and respiratory disturbances. Additionally, inhalation, oral intake, or skin absorption can result in irritation, pain, and allergic reactions.
d-Limonene is a liquid with a lemon-like smell, often used as a solvent to substitute for more volatile and toxic organic solvents. When it comes into contact with air, it can oxidize, and this oxidized form is a known skin sensitizer, capable of irritating skin and eyes. The combination of d-limonene and l-limonene is known as limonene or dipentene. The estimated lethal dose for humans is between 0.5 to 5 g/kg, and studies have shown that it can cause diarrhea and liver effects when ingested in high doses.
Phthalates, linked to endocrine disruption, reproductive toxicity, and cancer, are banned in the European Union but remain prevalent in U.S. cosmetics. They are widely used in personal care products, such as nail polish, fragrances, and eyelash glue and other products. A significant loophole allows phthalates to be added to fragrances without disclosure. Health concerns include endocrine disruption, developmental and reproductive toxicity, and potential carcinogenicity.
Campaign for Safe Cosmetics: Phthalates, Product Profile: Hand Sanitizer, Phthalates in Cosmetics, Phthalates in cosmetic and personal care products: concentrations and possible dermal exposure, A Survey of Phthalates and Parabens in Personal Care Products from the United States and Its Implications for Human Exposure, Phthalates Factsheet, BPA and Phthalates: Chemicals found in our homes
Butylparaben, a chemical used in various products, has been shown to cause skin irritation in humans and potential sensitization in dermatitis patients. Animal studies indicate that it has low to moderate oral toxicity and can cause damage to the liver, spleen, and thymus. It can also lead to cell proliferation in rats' stomachs, though it was not found to be carcinogenic or mutagenic. However, it may negatively impact sperm viability and activity, as demonstrated in different in vitro and in vivo studies. Lastly, it proposed weaker aquatic toxicity compared to parabens with longer alkyl chains, but still showed estrogenic effects in certain fish species.
Ethylparaben is a chemical used as a preservative in various products including pharmaceuticals, cosmetics, and adhesives. It exhibits low toxicity in humans and animals, but can cause skin irritation, particularly when applied to damaged skin, and may worsen pre-existing skin conditions. Despite causing cell proliferation in rats' forestomachs and chromosomal aberrations in a hamster ovary cell test, it has shown no evidence of causing cancer. However, it was found to be toxic to fetuses at doses toxic to the mother, though it did not cause malformations (nonteratogenic). Interestingly, while it impacted sperm viability in lab conditions, it showed no negative effects on mouse sperm in actuality.
Campaign For Safe Cosmetics: Parabens, Product Profile: Hand Sanitizer, Parabens At A Glance, What to Know About Parabens, The effects of ethylparaben and propylparaben on the development and fecundity of Drosophila melanogaster, Ethylparaben, Amended Safety Assessment of Parabens as Used in Cosmetics, WHAT ARE PARABENS: CHEMICAL FREE LIVING, Biomonitoring Summary
Methylparaben is an antimicrobial preservative used in food, drugs, and cosmetics. Some individuals can develop contact dermatitis on skin exposure, and allergic reactions have been reported on ingestion, though the evidence is not conclusive. Data from animal studies suggest that methylparaben is practically non-toxic and non-irritating in normal skin conditions, with high thresholds for observed adverse effects. However, it showed chromosome aberrations in a cell assay and variable results in different uterotrophic assays. An ecotoxicity study found changes in the expression of certain genes at specific concentrations in male medaka, a type of fish.
Propylparaben is a stable, non-volatile compound utilized as an antimicrobial preservative in food, drugs, and cosmetics. Human exposure can cause sensitization especially if applied to damaged skin and may cause contact sensitivity with high concentrations. Extensive animal studies reveal that propylparaben is relatively non-toxic, yet it can mildly irritate skin, affect sperm counts in substantial levels, and trigger cell proliferation in the forestomach of rats. However, it is not carcinogenic, mutagenic, or clastogenic, and a significant no-observed-adverse-effect level was reported in rats. Ecotoxicity studies show that it can lead to an increase in plasma vitellogenin levels in rainbow trout and a significant decline of vitellogenin production in zebrafish at varying concentrations.
Isobutylparaben belongs to the paraben family of preservatives used in the food, pharmaceutical, and personal care product industries. Parabens mimic estrogen and have been found in breast cancer tumors in some studies. Parabens are commonly found in various personal care products and foods and have been associated with endocrine disruption, skin cancer risk, developmental and reproductive toxicity, and potential behavioral changes in offspring when exposed during gestation.
Isopropylparaben belongs to the parabens family of preservatives utilized in the food, pharmaceutical, and personal care sectors. Parabens have estrogen-mimicking properties and pose a potential risk as endocrine disruptors. Research has detected parabens in the breast cancer tumors of a significant number of studied women, raising concerns about their safety and hormonal effects.
3-tert-Butyl-4-hydroxyanisole is a component of the food preservative Butylated Hydroxyanisole, used where Butylated hydroxytoluene is restricted. It serves as an oxidation inhibitor for human consumption. Despite lacking human studies, animal tests reveal no mutagenic activity. Its mutagenicity was evaluated using Salmonella typhimurium and Chinese hamster fibroblast cell line, with chromosomal aberrations induced only in the presence of the S9 mix.
BHT, a toluene-based ingredient, serves as a preservative in food and personal care products. Safety assessments have noted toxic effects in lung tissue when BHT was applied to rats' skin but considered the low concentrations in cosmetics safe. The American Conference of Governmental Industrial Hygienists (ACGIH) suggests moderate evidence of BHT being a respiratory irritant in humans.
1,4-Dioxane is a clear, water-soluble liquid that is primarily used as a solvent in chemical manufacturing and laboratory reagents. Other uses leverage its solvent properties, including cosmetics, detergents, and shampoos. However, manufacturers generally reduce 1,4-Dioxane to low levels in these products due to its potential health risks. Acute exposure can result in symptoms such as vertigo, drowsiness, and irritation of the eyes, nose, throat, and skin. Chronic exposure may lead to liver and kidney damage, and the substance is classified as a probable human carcinogen by the EPA. Notably, severe kidney and liver damage, CNS effects, and even death have been recorded after heavy or prolonged exposure.
What Is 1,4-Dioxane in Laundry and Cleaning Products?, Effect of ethoxylation and lauryl alcohol on the self-assembly of sodium laurylsulfate: Significant structural and rheological transformation, Final Risk Evaluation for 1,4-Dioxane, Ongoing and Completed Chemical Risk Evaluations under TSCA, Preliminary Information on Manufacturing, Processing, Distribution, Use, and Disposal, TOXICOLOGICAL REVIEW OF 1,4-DIOXANE, 15th Report on Carcinogens, 1,4-Dioxane, Determination of residual 1,4-dioxane in surfactants and cleaning agents using headspace single-drop microextraction followed by gas chromatography–flame ionization detection, 1,4-Dioxane in Cosmetics: A Manufacturing Byproduct, An integrated assessment of the 1,4-dioxane cancer mode of action and threshold response in rodents, Campaign for Safe Cosmetics: 1,4-DIOXANE, Product Profile: Hand Sanitizer, Occurrence of 1,4-dioxane in cosmetic raw materials and finished cosmetic products, Chemical Profile: 1,4-dioxane
Oral administration of high doses in adults causes ciricrhosis, hemorrhage, anorexia, jaundice, and dermatitis. The use of this substance is contraindicated in pregnancy at doses larger than the FDA recommend daily allowance. Ingesting 25,000 IU/d over a period of 2-3 weeks may result in toxicity, symptoms of which include liver injury and increased intracranial pressure, leading to blurred vision, headaches, and changes to mental status. The substance is also found to be an irritant and harmful if ingested, with teratogenic effects observed in experimental animals.
Ethylene oxide is a flammable, sweet-smelling gas that easily dissolves in water. This man-made compound is primarily used to create ethylene glycol, which is used to make antifreeze and polyester, and is also used in small quantities for controlling insects in stored agricultural products, sterilizing medical equipment and fumigating spices. Ethylene oxide may cause irritation of the eyes, skin, nose, throat, and lungs, damage to the brain and nervous system, reproductive effects, and is considered by the EPA to be carcinogenic if inhaled. Exposure risks, which are notably prevalent for healthcare workers engaged in sterilization tasks, include CNS depression, eye and mucous membrane irritation and in some cases, cataracts. Despite these hazards, there are conflicted reports regarding ethylene oxide's carcinogenicity in humans.
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