The Welpr Rating is determined by a scoring formula. The formula takes into account the products safety, user satisfaction, and eco-ethical standing. Click here to learn more.
Best Non-Toxic Laundry Detergent in 2024
Written by Camille May
Cofounder & Product Curator
Medically reviewed by Olushola Awoyemi
PhD Environmental Toxicology
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What you should know when choosing non-toxic laundry detergent on Welpr:
- Only the cleanest products make it onto Welpr.
- We use a score called the Welpr Rating to rank each product.
- The Welpr Rating is based on math, not opinion, ensuring it's free from human bias.
Find Non-Toxic Laundry Detergent
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User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Nature+ Laundry Detergent, Unscented - Attitude
Certifications
Highlights
User Satisfaction
Est. Price
$24.37
Product Details
- EWG Verified for clean ingredients and full transparency.
- Made with ≥ 98% naturally sourced ingredients.
- Dermatologically tested for skin safety.
- Formulated with powerful naturally sourced surfactants for excellent detergent power.
- Effective for cold water wash, saving energy.
- Packaging is made from easily recyclable HDPE #2 plastic.
- 100% vegan and cruelty-free, certified by PETA.
- Gentle on skin.
Pros & Cons
Pros Mentioned
- Effective
- Gentle
- Non-toxic
Cons Mentioned
- Inconsistent
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: 5%-15% Anionic Surfactants (Sodium Coco-Sulfate), 5%-15% Non-Ionic Surfactants (Lauryl Glucoside, Caprylyl Glucoside, Myristyl Glucoside), Contains Also: Water, Sodium Chloride, Citric Acid, Sodium Gluconate, Sodium Benzoate, Glycerin, Camellia Sinensis Leaf (Green Tea/Thé Vert) Extract, Ethylene Brassylate, Ethyl Linalool, Methyldihydrojasmonate, Benzyl Acetate, Dimethyl Heptenal, Fragrance
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Original Laundry Detergent Powder, Unscented - Molly's Suds
Certifications
Highlights
User Satisfaction
Est. Price
$22.99
Product Details
- Contains five stain-fighting, natural ingredients safer for both family and the environment.
- Provides powerful cleaning with just one tablespoon-sized scoop per load.
- Gentle on sensitive skin and most fabrics, except silk and leather.
- Free from artificial dyes and fragrances to ensure compatibility with sensitive skin.
- Manufactured in the USA using plant and earth-derived active cleaning ingredients.
- Products are peanut-free, vegan, and certified cruelty-free by Leaping Bunny.
- Leaves no residue and rinses cleanly, making it suitable for septic and grey water systems.
- Works effectively in all types of washing machines including standard, commercial, and high efficiency (HE).
- Formulated to minimize suds, eliminating buildup left by previous detergents.
- Included in the package: One 79 oz bag capable of handling up to 120 laundry loads.
- Sustainable laundry option, free of harsh synthetic fragrances, dyes, and harmful additives.
Pros & Cons
Pros Mentioned
- Effective
- Gentle
- Non-toxic
Cons Mentioned
- Residue
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Sodium Carbonate, Sodium Bicarbonate, Magnesium Sulfate (Heptahydrate), Unrefined Sea Salt, Organic Peppermint (Mentha Piperita) Oil
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Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Laundry Soda, Unscented - Nellie's
Certifications
User Satisfaction
Est. Price
$13.50
Product Details
- Concentrated cleaning power for effective stain removal.
- Quick dissolving formula works in both cold and hot water.
- Leaves no residue, ensuring clothes and linens are rinsed completely clear.
- Gentle on skin and environmentally friendly with a non-toxic, hypoallergenic, fragrance-free, and biodegradable formula.
- No fillers are used in its composition.
- HE certified, suitable for High Efficiency wash machines.
- Suitable for everyday materials including silk, wool, cashmere, and other delicate fabrics.
- Incorporates a small amount of water softener, suitable for areas with moderately hard water.
- PH balance of 10.5-11.9.
Pros & Cons
Pros Mentioned
- Effective
- Gentle
- Eco-friendly
Cons Mentioned
- Packaging
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Sodium Carbonate, Linear Alcohol Ethoxylate, Sodium Chloride, Sodium Metasilicate
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Concentrated Laundry Detergent, Soft Lavender - Hello Bello
Certifications
Highlights
User Satisfaction
Est. Price
$12.99
Product Details
- Made with organic soap berries and botanical extracts.
- Features a lavender scent derived from natural essential oils.
- Leaping Bunny Certified, indicating the product is not tested on animals.
- Recognized as a Parent Tested, Parent Approved Winner.
- USDA Biobased 100% certified, ensuring a high level of biobased content.
- Formulated to be gentle on baby-related fabrics yet powerful on stains.
- Septic system safe and suitable for high-efficiency washing machines.
- Bottle is composed of 50% sugar cane resin, reflecting eco-friendly packaging practices.
- Free from synthetic fragrances, dyes, and artificial brighteners.
- Part of a brand mission to provide high-quality, affordable products for all families.
- Involved in charitable efforts, with over 6 million diapers donated to families in need.
Pros & Cons
Pros Mentioned
- Gentle
- Effective
- Scented
Cons Mentioned
- Ineffective
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, Organic Sapindus Mukorossi (Soapberries) Extract, Cocos Nucifera (Organic Coconut) Oil & Potassium Hydroxide*, Sodium Citrate, Organic Lonicera Japonica (Honeysuckle) Flower Extract, Xanthan Gum, Alcohol (Organic), Sodium Chloride, Sodium Carbonate, Glycerin (Organic), None Remains In Finished Product.
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Bio Enzyme Detergent, Free & Clear - Dirty Labs
Certifications
Highlights
User Satisfaction
Est. Price
$14.99
Product Details
- Consciously formulated with nontoxic, biobased ingredients for safe use on sensitive skin and all clothing types.
- Cruelty-free, vegan, hypoallergenic, and safe for babies and pets.
- Features Phytolase, an advanced enzyme cleaning technology that targets stains and odors effectively while being gentle on clothes and the planet.
- Environmentally friendly with hyper-concentrated formulas that reduce packaging sizes and carbon footprints.
- Bottles are made of aluminum and are designed for infinite recycling.
- Ingredients are responsibly sourced and created through biorenewable manufacturing processes.
- Compatible with both traditional and high-efficiency (HE) washers.
- Optimized for use with cold water.
- Certified EPA Safer Choice Partner and contains 97% USDA Biobased certified ingredients.
- Free from sulfates, dyes, parabens, preservatives, chlorine bleach, and CA Prop.65 chemicals.
Pros & Cons
Pros Mentioned
- Efficient
- Gentle
- Eco-friendly
Cons Mentioned
- Pricey
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Caprylyl/Capryl Glucoside, Lauryl Glucoside, Capryloyl/Caproyl Methyl Glucamide, Protease, Amylase, Pectate Lyase, Mannanase, Cellulase, Coconut Fatty Acids, Propanediol, Sodium Citrate, Glycerin, Potassium Hydroxide, Aqua
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Laundry Powder Detergent, Unscented - Meliora Cleaning Products
Certifications
Highlights
User Satisfaction
Est. Price
$22.99
Product Details
- Concentrated powder formula reduces the need for preservatives and diminishes plastic waste.
- Packaged in recyclable paper and steel canister with a stainless steel scoop, avoiding plastic use.
- Contains baking soda, washing soda, and organic coconut oil-based soap with no added fragrances.
- Provides sufficient detergent for 128 HE loads using only half a tablespoon per load in HE washers.
- Manufactured in the USA by a woman-owned, B Corp Certified small business.
- All ingredients are MADE SAFE certified, Leaping Bunny certified, and vegan-friendly.
- Contributes 2% of annual revenue to environmental causes.
- Instructions include measuring with stainless steel scoop and adding powder directly to the washer drum for optimal results.
- Refillable packaging design allows canister reuse with refill bags, reducing overall packaging produced.
- Non-toxic ingredients include sodium bicarbonate and sodium cocoate, ensuring safety and effectiveness without harming health or ecosystems.
- Entire product is cruelty-free and does not contain any synthetic fragrances, using organic essential oils in scented varieties.
- Designed for recyclability, instructs users on how to separate packaging materials for recycling.
Pros & Cons
Pros Mentioned
- Eco-friendly
- Effective
- Smells great
Cons Mentioned
- Residue
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Sodium Bicarbonate (Baking Soda), Sodium Carbonate (Washing Soda), Sodium Cocoate (Vegetable Soap), Cocos Nucifera Oil (Organic Coconut Oil), Glycerin
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Liquid Laundry Detergent, Eucalyptus - 9 Elements
Certifications
User Satisfaction
Est. Price
$15.99
Product Details
- Vinegar-powered: Strips away trapped residues and odors with the purifying power of vinegar, leaving no vinegar odor.
- Limited ingredients: Contains no artificial preservatives, dyes, thickeners, or brighteners.
- Sensitive skin friendly: Gentle formula designed for sensitive skin.
- EPA Safer Choice label: Meets criteria for environmental and human health protection.
- Plant derived ingredients: 50% of ingredients are sourced from plants.
- Effective in hard water: Removes buildup from hard water, ensuring a thorough clean.
Pros & Cons
Pros Mentioned
- Effective
- Non-toxic
- Fresh
Cons Mentioned
- Pricey
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, Citric Acid, C12-16 Pareth, Sodium C10-16 Alkylbenzenesulfonate, Propylene Glycol, Lemon Essential Oil, Sodium Citrate, Vinegar
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Laundry Detergent Tablets, Free & Clear - Blueland
Certifications
Highlights
User Satisfaction
Est. Price
$29.99
Product Details
- Plastic-free and eco-friendly alternative to conventional laundry detergent forms such as pods and liquids.
- 100% plastic-free, eliminating the plastic film found in most conventional detergent pods.
- Powered by enzymes for effectiveness in lifting tough stains like grass, coffee, food, and makeup, while maintaining color vibrancy and whiteness.
- Simple usage: drop one tablet in the washing machine drum before adding clothes; use two tablets for large loads.
- Composed of hypoallergenic, plant and mineral-based ingredients without fragrances, dyes, or optical brighteners.
- Safe for both children and pets, bearing certifications such as EPA Safer Choice, Leaping Bunny Cruelty-Free, Vegan, B Corp Certified, Climate Neutral, and USDA Bio-Preferred.
Pros & Cons
Pros Mentioned
- Eco-friendly
- Effective
- Compact
Cons Mentioned
- Undissolved
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Sodium Carbonate, Citric Acid, Microcrystalline Cellulose, Subtilisin, Lauryl/Myristyl Glucoside, Amylase, Sorbitan Caprylate, Mannanase, Sodium Citrate, Cellulase, Hydrated Silica
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Laundry Detergent, Unscented - Greenshield Organic
Certifications
User Satisfaction
Est. Price
$24.99
Product Details
- Made with USDA certified organic ingredients.
- Bottled using sustainable, recyclable sugar cane.
- Leaves no residue on clothing or in the washing machine.
- Does not damage water quality.
- Free from phosphates and petrochemicals.
- Effective in both HE and standard machines on colors and whites.
- Suitable for people with sensitive skin and allergies.
- Does not contain added fragrances.
- Ingredients include organic soap berries, saponified organic coconut oil, and organic aloe vera.
- GMO free.
Pros & Cons
Pros Mentioned
- Organic
- Unscented
- Effective
Cons Mentioned
- Expensive
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, Sodium Laureth Sulfate, Glycerin, Sodium Chloride, Lauryl Glucoside, Sodium Citrate, Protease Enzyme Blend, Amylase Enzyme Blend, Lipase Enzyme Blend, Pectate Lyase Enzyme Blend, Mannanase Enzyme Blend, Sodium Bicarbonate, Benzisothiazolinone, Citric Acid
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Laundry Detergent Pods , Unscented - AspenClean
Certifications
User Satisfaction
Est. Price
$19.99
Product Details
- Packaged in 100% recycled paper container, fully compostable
- Made with biodegradable, plant-based ingredients for a deep and powerful clean
- Tough on stains, effective in removing dirt, grime, and grease, while being safe for sensitive skin, babies, and pets
- Fragrance-free, using no synthetic fragrances, toxins, or irritants
- Contains oxygen bleach and enzymes for natural cleaning
- No harsh chemicals used, ensuring safety and environmental sustainability
- Certified by EcoCert for organic home care standards
- EWG Verified with an A-rating, highlighting commitment to health and environmental standards
Pros & Cons
Pros Mentioned
- EWG-certified
- Effective
- Unscented
Cons Mentioned
- Non-dissolving
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Sodium Carbonate, Sodium Citrate, Sodium Carbonate Peroxide, Sodium Sulfate, Sodium Oleate (Vegetables Derived), Sodium Chloride (Salt), Decyl Glucoside (Coconut, Palm Kernel Oil Derived), Water / Eau, Protease (Enzyme), Hydrated Silica, Alpha-Amylase (Enzyme), Cocos Nucifera (Coconut) Oil, Mannanase (Enzyme), Alcohol (Corn Derived), Cellulase (Enzyme)
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Fresh Laundry Detergent, Peppermint & Lemon - Rebel Green
Certifications
Highlights
User Satisfaction
Est. Price
$39.95
Product Details
- Made with a 3x concentrated formula for effective cleaning
- Utilizes USDA certified organic surfactants
- Scented with essential oils for a pleasant aroma
- Formulated to be gentle on the skin and ideal for those with sensitive conditions
- Ingredients are sustainably sourced and environmentally friendly
- Supports environmental causes with donations from each product sold
- Part of a broader range of natural cleaning products aimed at promoting a healthier lifestyle
Pros & Cons
Pros Mentioned
- Cleans
- Organic
- Non-toxic
Cons Mentioned
- Watery
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, Sapindus Mukorossi Fruit (Organic Soap Berry) Extract, Cocos Nucifera Oil & Potassium Hydroxide* (Saponified Organic Coconut Oil), Sodium Citrate, Lonicera Japonica (Organic Honeysuckle) Flower Extract, Xanthan Gum, Mentha Piperitas And Citrus Limon Peel Oil (Fragrance), Organic Acacia Senegal Oil, Organic Guar Gum, Sodium Carbonate, Sodium Chloride
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Laundry Detergent Strips, Original - Lazy Coconuts
Certifications
User Satisfaction
Est. Price
$14.95
Product Details
- Powered by coconut-derived soap, the detergent strips are cruelty-free, vegan, and free of dye, perfume, parabens, phthalates.
- Designed for deep cleaning, the strips effectively remove odors, stains, and dirt from clothes.
- Suitable for both machine and hand washing, ideal for travel and outdoor use like camping.
- Product packaging is carbon negative, ultra low emission, and includes offsetting emissions by 2x through The Gold Standard and UNFCC.
- The detergent strips are biodegradable with 100% recyclable cardboard packaging and contain no plastic, preventing microbead pollution.
- Comes with a satisfaction guarantee offering a full refund within 30 days if not satisfied.
- Tested to ensure no animal testing is performed at any stage of product development.
Pros & Cons
Pros Mentioned
- Effective
- Portable
- Eco-friendly
Cons Mentioned
- Weak
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Sodium Lauryl Sulfate, Kaolin, Water, Polyvinyl Alcohol, Cocamide, Alcohols C12-18, Ethoxylated, Silicon Dioxide, Bentonite, Glycerol, Trisodium Citrate, 1,2-Benzisothiazolin-3-One, Saponins
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Laundry Nuggets, Fragrance Free - Nellie's
Certifications
User Satisfaction
Est. Price
$14.55
Product Details
- Utilizes a plant-based, biodegradable formula that is vegan-friendly and designed for effective, gentle cleaning.
- Comes in pre-measured nuggets to eliminate the need for measuring, minimizing waste and preventing spills.
- Quickly dissolves in both hot and cold water without leaving any residue, suitable for both home use and travel.
- Eco-friendly product that ensures thorough rinse, leaving clothes free from harsh chemicals and residues.
- Travel-friendly packaging, ideal for maintaining cleanliness during trips without the hassle of measuring detergent.
- Provides effective stain removal and freshening for up to 36 loads while adhering to sustainability and eco-conscious practices.
- HE certified, supporting high efficiency washing machines.
- The nugget film is made from MonoSol PVA, a water-soluble film that dissolves completely without negative environmental impact or contributing to microplastic pollution.
- All of Nellie's laundry products are septic safe.
Pros & Cons
Pros Mentioned
- Convenient
- Natural
- Effective
Cons Mentioned
- Indissoluble
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Soda Ash, Linear Alcohol Ethoxylate, Sodium Chloride, Sodium Metasilicate, Sodium Carbonate, MonoSol Film
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Vegan Laundry DEDtergent, Spring - Dedcool
Highlights
User Satisfaction
Est. Price
$35.00
Product Details
- Allows customization of scent when combined with compatible dryer sheets and fragrances.
- Average customer review rating of 4.1 out of 5 stars.
- Top scent notes include bergamot, fresh dew, cardamom, and star anise.
- Middle scent notes feature white musk, floral, cassis, geranium, incense, lavender, and woods.
- Bottom scent notes of amber, vanilla, moss, patchouli, vetiver, and wild berries.
- Described as evoking feelings of warmth, clean skin, a fresh start, and optimism.
- Available as eau de parfum, room and linen spray, and pet fragrance.
- Promoted as genderless, all-natural, and vegan.
- Portable fragrance spray suitable for multiple living spaces.
- Pet fragrance is gentle, made with organic and natural plant extracts, non-toxic and vegan.
- Products are not tested on animals.
- Packaging is designed to be recyclable and reusable, with plans for more bulk product releases.
- Shelf life of fragrances is 12 months, with a note that color may change if exposed to direct sunlight or fluorescent lighting.
- The scent and other products are designed to last for 12 months after opening.
Pros & Cons
Pros Mentioned
- Scent
- Soft
- Stylish
Cons Mentioned
- Inconsistent
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water (Aqua), Coco-Glucoside, Fragrance (Parfum), Caprylhydroxamic Acid (And) Caprylyl Glycol* (And) Glycerin*, Carbomer*
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Sensitive Skin Laundry Detergent, Signature Scent - Truly Free
Certifications
Highlights
User Satisfaction
Est. Price
$39.95
Product Details
- Includes one reusable jug and three powder sachets for up to 150 loads of laundry
- Designed for sensitive skin: non-toxic and free from harsh chemicals, thickeners, dyes, optical brighteners, or synthetic fragrances
- Hypoallergenic formula suitable for people with allergies or sensitivities
- Plant-based ingredients, promoting eco-friendly and sustainable laundry practices
- Supports social impact projects that empower women and children in need
- Animal cruelty-free, ensuring no animals were harmed in the making of the product
- Travel-friendly design allows for easy transportation and usage while on-the-go
- Produced in the USA, ensuring domestic sourcing and manufacturing quality
Pros & Cons
Pros Mentioned
- Effective
- Fresh-smelling
- Non-toxic
Cons Mentioned
- Pricey
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Tetrasodium Salt, Sodium Dodecylbenzenesulfonate, Sodium Citrate, Sodium Polyacrylate, Sodium Cocoate, Sodium Carbonate, Alkyl Polyglucoside, Dodecyl Benzene Sulfonic Acid (DDBSA), Sodium Lauryl Sulfoacetate, Clove Leaf Oil-Plant Based, Eucalyptus Oil-Plant Based, Lavandin Grosso-Plant Based, Fir Needle Oil-Plant Based, Lime Oil-Plant Based, Precipitated Silica
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Plant-Based Laundry Detergent, Orange Blossom & Citrus Leaves - Botanical Origin
User Satisfaction
Est. Price
$20.80
Product Details
- Removes tough stains using a plant-based formula with a quadruple-enzyme system effective against common stains like coffee, wine, and spaghetti sauce.
- Free from dyes, brighteners, chlorine, phosphate, and artificial preservatives for a cleaner laundry process.
- Designed for sensitive skin: hypoallergenic and dermatologist tested formula.
- Offers scents inspired by nature, including options like Orange Blossom & Citrus Leaves and Fresh Jasmine & Wild Lavender, combined with hypoallergenic properties.
- Compatible with all water temperatures and can be used in regular washers, high-efficiency (HE) washers, and for hand washing.
- Provides a plant-based cleaning solution without compromising on performance.
Pros & Cons
Pros Mentioned
- Gentle
- Effective
- Refreshing
Cons Mentioned
- Expensive
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, C12-14 Alcohols Ethoxylate, Sodium Laureth Sulfate, Glycerin, Tea Cocoate, Sodium Citrate, Fragrance, Sodium Diethylenetriamine Pentamethylene Phosphonate, Protease Enzyme, Copolymer Of 1-Vinylimidazole And 1-Vinyl-2-Pyrrolidone, Amylase, Cellulase, Mannanase
Our Product Rating System
First, Camille (co-creator of Welpr) hand picks cleaner product options from a variety of sources.
Next, we collect information about each product's safety, consumer satisfaction, and eco-ethical standing.
Finally, we run all this information through an algorithm that calculates the Welpr Rating.
Welpr Rating:
5.0/5
Part 1: Product safety
We evaluate safety information from 3rd party organizations (e.g. EWG, Made Safe, etc.). Instead of relying solely on any one of these companies for safety information, we assess all of them.
Part 2: Consumer satisfaction
We scour the web for consumer ratings and reviews to verify products are not only cleaner options, but also effective. Products can either be Above Average, Average, or Below average for their respective category (e.g. cleaning products).
Part 3: Ethics & Environment
When you buy a product, you’re supporting that company with your dollars. We believe it’s important to support ethical companies, so we pool together certifications that verify a company's ethics and environmental impact.
Common Harmful Chemicals in Laundry Detergent
Chemical Name
Why it’s harmful
Sodium Laureth Sulfate
Sodium laureth sulfate, derived from ethoxylated lauryl alcohol, is a surfactant used in sudsy products like toothpaste, detergents, and shampoos. While it acts as a cleansing and emulsifying agent, it can sometimes contain toxic impurities such as 1,4-dioxane. This chemical has raised health concerns due to its potential to cause skin, lung, and eye irritation, organ toxicity, and, primarily because of contamination by 1,4 dioxane, cancer.
Sources:
The Dirty Dozen: Sodium Laureth Sulfate, 15 Toxic Trespassers, SKIP PRODUCTS MADE WITH SLES (AND SLS, TOO!), Campaign for Safe Costmetics: 1,4-DIOXANE, WHAT IS SODIUM LAURETH SULFATE: CHEMICAL FREE LIVING, A new formula for a mild body cleanser: sodium laureth sulphate supplemented with sodium laureth carboxylate and lauryl glucoside,
Sodium Lauryl Sulfate
Sodium Lauryl Sulfate is recognised as a skin, eye, and respiratory tract irritant according to ICSC. It may cause allergic reactions and eye irritation as stated by the HSDB. Exposure may even result in eye burns, as per CAMEO. Depending on its form - which may range from a solid (90-98% purity), to a paste (30-41%), or an aqueous solution (28-50%) - it can significantly irritate skin and eyes, with adverse effects escalating with increased concentration. Despite these hazards, it is not a skin sensitizer according to CHEMINFO, while eChemPortal: ERMA and MSDSonline endorse its classification as an irritant.
Nonylphenol ethoxylate
Nonylphenol ethoxylate, commonly found in cleaning products, has been linked to allergic contact dermatitis among workers. It is a strong eye irritant, causing mild to severe eye irritation, possible corneal injury, and mild skin irritation. Inhalation can be harmful. It has been shown to cause changes in liver functions and have demonstrated effects on the liver, kidney, and fetus at doses that are toxic to mothers (maternally toxic) in non-mammalian species. Despite these effects, there is no reported teratogenicity, carcinogenicity, or skin sensitization associated with nonylphenol ethoxylate in experimental animals and human studies.
Sources:
Benzene
Benzene is a colorless, sweet-smelling, highly flammable liquid that evaporates quickly into the air and slightly dissolves in water. It's a byproduct of both natural processes and human activities, used extensively in the U.S production of other chemicals for plastics, resins, nylon, rubbers, lubricants, dyes, detergents, drugs, and pesticides. Present in crude oil, gasoline, and cigarette smoke, benzene is also released into the air from burning coal, oil, gasoline stations, and vehicle exhaust. Short-term exposure may cause drowsiness, dizziness, and irritation, while long-term exposure leads to blood disorders, reproductive effects, and even leukemia. Benzene has been classified by EPA as a known human carcinogen, and regulations apply to various industry sectors with potentially high exposure risks.
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DMDM hydantoin
DMDM hydantoin is a substance used in cosmetics that has the potential to cause allergic contact dermatitis, although rinse-off products generally have a low risk. According to various reports, skin sensitization patch testing has yielded positive results.
Imidurea
Imidurea is a compound used in cosmetics known to potentially cause allergic contact dermatitis. However, the risk of this condition is generally low with rinse off products. Although there have been reports of contact dermatitis caused by its use in cosmetics, some studies have not observed any contact sensitivity. It is identified as an irritant based on Aldrich Material Safety Data Sheet.
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Quaternium-15
Quaternium-15 is a preservative commonly used in cosmetics which is known to significantly contribute to allergic contact dermatitis in users. This condition has been reported in various professions, including hairdressers, machine maintenance engineers at a chicken processing plant, and photocopy workers. Notably, Quaternium-15, as a formaldehyde releaser, increases dermatitis risk. However, rinse-off products typically pose a lower risk of resulting in allergic contact dermatitis.
Diethanolamine
Diethanolamine is a chemical found in various consumer products like shampoos, cosmetics, and pharmaceuticals. Acute exposure in humans can result in irritation of the nose, throat, and skin. However, no detailed data is available on its chronic, reproductive, developmental or carcinogenic effects on humans. Studies on animals reveal that acute oral exposure can influence the liver, blood, kidney, and central nervous system, while dermal exposure has been connected with an increased incidence of liver and kidney tumors in mice. Production of first-degree burns, skin irritation, occupational asthma, kidney, and liver injury risk, and potential skin sensitization are some other adverse effects associated with diethanolamine.
Sources:
Chemical Safety Facts: Ethanolamines, NTP Toxicology and Carcinogenesis Studies of Diethanolamine, California Environmental Protection Agency: Diethanolamine , International Agency for Research on Cancer: Diethanolamine, Initial List of Hazardous Air Pollutants with Modifications, What is the Toxics Release Inventory?, OPINION CONCERNING DIALKYL- AND DIALKANOLAMINES AND THEIR SALTS IN COSMETIC PRODUCTS, Ethanolamine Compounds (MEA, DEA, TEA And Others), WHAT ARE ETHANOLAMINE COMPOUNDS (DEA, MEA, OR TEA): CHEMICAL FREE LIVING, The Dirty Dozen: DEA-related ingredients, FDA: Diethanolamine, Chemical Profile: Diethanolamine ,
VOCs (Volatile Organic Compounds)
Volatile organic compounds (VOCs) are released by many cleaning products, as revealed by a study in Chemosphere which analyzed 30 such items. Of the 530 distinct VOCs identified, 193 were considered hazardous, linked to health issues like respiratory system damage and cancer. Indoor air contamination from VOCs is significantly higher than outdoor, with up to 10 times more pollutants. However, products labeled as green, particularly those without fragrances, exhibited fewer hazardous VOC emissions. Exposure to VOCs has critical health implications, especially for cleaning industry workers and children, and these compounds also contribute to outdoor air pollution.
2-Nonylphenol
Monoalkyl phenols are primarily para substituted technical mixtures that have isomeric branched-alkyl radicals as side chains. This compound is corrosive to skin and can cause first-degree burns with short-term exposure. High inhalation can result in respiratory tract irritation, potentially leading to corrosive injuries to the upper respiratory tract and lungs. Moreover, it is harmful upon ingestion.
Benzyl Alcohol
Benzyl alcohol can occasionally lead to allergic contact dermatitis or occupational contact urticaria. It can irritate the skin and eyes, and inhalation at high quantities can result in central nervous system effects. Rats exposed to high concentrations showed no deaths, however, it has caused fatalities in premature infants when given in IV solutions at doses over 4.5mg/kg a day. The substance is quickly metabolized to hippuric acid and is noted as a known contact allergen in humans.
Benzisothiazolinone
Isothiazolinones are preservatives known to cause allergic contact dermatitis, primarily in workers involved in manufacturing industries like paint, paper, rubber, and air fresheners. Additionally, there's a reported case of occupational asthma from exposure to this chemical among workers.
Stearyl Alcohol
Stearyl Alcohol is not significantly toxic in industrial settings, although it can cause liver injury, somnolence, and respiratory depression in experimental animals. It can also induce somnolence in lethal-dose feeding studies on rats. Despite extensive research, no effects of short-term or long-term exposure to these substances have been identified in humans. However, higher alcohols can be irritants.
Denatonium Benzoate
Denatonium Benzoate causes somnolence, tremor, and ataxia in rabbits and rats according to oral lethal-dose studies and is harmful by ingestion. It is one of the most bitterly known substances, with a 1980 case report linking it to urticaria and asthma. The European Union classifies it as highly toxic by inhalation and a potential cause of serious eye injury. Lastly, it is a strong eye irritant and skin irritant according to the Sigma-Aldrich Material Safety Data Sheet.
Disodium Distyrylbiphenyl Disulfonate
Disodium Distyrylbiphenyl Disulfonate does not cause skin irritation but can cause serious eye irritation in rabbits, as classified by the EC. It does not trigger skin sensitization in guinea pigs, yet it can lead to somnolence and dyspnea when inhaled in high concentrations by rats. While certain sources note it may cause transient eye irritation without any skin irritation or sensitization, it is confirmed that a 29-31% aqueous solution of the same is indeed an eye irritant.
Dimethyldioctadecylammonium Chloride
Dimethyldioctadecylammonium chloride is a skin irritant and can cause serious eye injury. It's typically not available as an isolated compound but primarily found in dihydrogenated tallow dimethyl ammonium chloride (DHTDMAC). DHTDMAC is a substance containing variable proportions of similar compounds having carbon chains ranging from C12 to C20. It can be commercially obtained in different forms like a paste-like substance, powder, or aqueous emulsion, with varying percentages of dimethyldioctadecylammonium chloride. Studies on rabbits demonstrated that technical grade DODMAC, which has 77% dimethyldioctadecylammonium chloride, was corrosive to skin and the pure compound could cause moderate skin irritation along with severe eye damage.
Formaldehyde
Formaldehyde is a colorless, flammable gas with a pungent smell that's naturally produced in small quantities in human bodies and is also known as methanal amongst other names. It's used in the production of various items such as fertilizers, paper, plywood, and urea-formaldehyde resins as well as in some foods and household products like antiseptics, medicines, and cosmetics. Exposure to formaldehyde, which can occur through breathing contaminated indoor air, tobacco smoke, or ambient urban air can lead to respiratory symptoms, irritation of the eyes, nose and throat and has been linked to lung and nasopharyngeal cancer as well as leukemia. The EPA considers formaldehyde a probable human carcinogen (Group B1) and inhaling it can cause bronchospasm and pulmonary edema. Commercially, it's sold as formalin in solutions of 37%, 44%, or 50% and long-term exposure can cause first-degree burns, skin sensitization, squamous cell nasal cancer, and chronic pulmonary obstruction.
Sources:
Formaldehyde and Cancer Risk, Cleaning Products & Indoor Air Quality, No More Toxic Tub, Campaign for Safe Cosmetics: Preservatives, Campaign for Safe Cosmetics: Formaldehyde And Formaldehyde-Releasing Preservatives, Formaldehyde may be found in cosmetic products even when unlabelled, Formaldehyde Found in Popular American Beauty Products, Hair Salons - Formaldehyde in Your Products, Formaldehyde in cosmetic products
Butylphenyl Methylpropional
Butylphenyl methylpropional, also known as lilial, is a chemical compound commonly used in cosmetics and laundry powders. It is found naturally in crow-dipper and tomato plants and is also produced synthetically in large quantities. In May 2019, the EU's Scientific Committee on Consumer Safety (SCCS) deemed its use in cosmetics as unsafe. Following animal studies indicating reproductive toxicity, the EU banned its use in cosmetics by March 2022. Moreover, butylphenyl methylpropional can sometimes serve as an allergen, potentially leading to contact dermatitis in susceptible individuals.
Sources:
Fragranced consumer products: exposures and effects from emissions, 10 reasons to avoid synthetic fragrances in cleaning products, Synthetic chemical in consumer products linked to early death, study finds, Review of the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens, Expert Panel Confirms that Fragrance Ingredient Can Cause Cancer, Fragrances, Beyond the Label: Health Impacts of Harmful Ingredients in Cleaning Products
Laureth-7
Laureth-7, a surfactant derived from lauryl alcohol sourced from coconut or palm oil, is commonly used in personal care and household products, especially laundry detergents. In detergents, it functions by reducing surface tension between water and soil, aiding in the removal of dirt, stains, and oils from fabrics. This ingredient belongs to the Polyethylene Glycols (PEGs) family, which is found in various consumer goods. Despite past contamination concerns, modern manufacturing processes have addressed and eliminated these issues. Although PEGs are not used in certain personal care products, their inclusion in machine detergents is deemed acceptable since they don't directly touch the skin.
d-Limonene
d-Limonene is a liquid with a lemon-like smell, often used as a solvent to substitute for more volatile and toxic organic solvents. When it comes into contact with air, it can oxidize, and this oxidized form is a known skin sensitizer, capable of irritating skin and eyes. The combination of d-limonene and l-limonene is known as limonene or dipentene. The estimated lethal dose for humans is between 0.5 to 5 g/kg, and studies have shown that it can cause diarrhea and liver effects when ingested in high doses.
Methylchloroisothiazolinone
5-chloro-2-methyl-4-isothiazolin-3-one (CMI) is a compound frequently used as a preservative in cosmetics, hygiene products, and other industrial applications such as hydraulic fracturing fluids. It can also be deployed as a pesticide in the U.S, pending regulatory approval. CMI, which is often used in combination with 2-methyl-4-isothiazolin-3-one (MI), can cause contact dermatitis in humans. Various animal studies have shown that a high exposure to a CMIT/MIT mixture can cause alterations in rats' liver function. The production and use of CMI in a range of products mean it can be release into the environment, with some susceptibility to degradation through photolysis in sunlight. Its mobility in soil is high but volatilization from soil or water surfaces is not expected to be significant. Occupational and general exposure to CMI can occur especially through inhalation and dermal contact with CMI-containing products.
Sources:
Antimicrobial agents, triclosan, chloroxylenol, methylisothiazolinone and borax, used in cleaning had genotoxic and histopathologic effects on rainbow trout, Methylisothiazolinone toxicity and inhibition of wound healing and regeneration in planaria, Methylchloroisothiazolinone and/or methylisothiazolinone in cosmetic products, Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles, Methylisothiazolinone and isothiazolinone allergy, Analysis of isothiazolinones in environmental waters by gas chromatography–mass spectrometry, Methylisothiazolinone induces apoptotic cell death via matrix metalloproteinase activation in human bronchial epithelial cells, EU REGULATIONS , Methylisothiazolinone contact allergy: a review, Effects of methylisothiazolinone and octylisothiazolinone on development and thyroid endocrine system in zebrafish larvae, Two Cases of Chloromethylisothiazolinone and Methylisothiazolinone-associated Toxic Lung Injury, An update of the risk assessment for methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) with focus on rinse-off products, Effects of a mixture of chloromethylisothiazolinone and methylisothiazolinone on peripheral airway dysfunction in children, Isothiazolinone preservative: cause of a continuing epidemic of cosmetic dermatitis, Campaign for Safe Cosmetics: Methylisothiazolinone and Methylchloroisothiazolinone
Methylisothiazolinone
Methylisothiazolinone can reportedly cause allergic contact dermatitis in workers who interact with products containing it. This substance is recognized as a contact allergen for consumers using cosmetics that include it. It can cause skin burns and sensitization, and inhaling it may lead to corrosive injuries in the upper respiratory tract and lungs. Ingesting this substance is harmful, and inhalation is toxic. This preservative is linked to the category of isothiazolinones.
Sources:
Antimicrobial agents, triclosan, chloroxylenol, methylisothiazolinone and borax, used in cleaning had genotoxic and histopathologic effects on rainbow trout, Methylisothiazolinone toxicity and inhibition of wound healing and regeneration in planaria, Methylchloroisothiazolinone and/or methylisothiazolinone in cosmetic products, Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles, Methylisothiazolinone and isothiazolinone allergy, Analysis of isothiazolinones in environmental waters by gas chromatography–mass spectrometry, Methylisothiazolinone induces apoptotic cell death via matrix metalloproteinase activation in human bronchial epithelial cells, EU REGULATIONS , Methylisothiazolinone contact allergy: a review, Effects of methylisothiazolinone and octylisothiazolinone on development and thyroid endocrine system in zebrafish larvae, Two Cases of Chloromethylisothiazolinone and Methylisothiazolinone-associated Toxic Lung Injury, An update of the risk assessment for methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) with focus on rinse-off products, Effects of a mixture of chloromethylisothiazolinone and methylisothiazolinone on peripheral airway dysfunction in children, Isothiazolinone preservative: cause of a continuing epidemic of cosmetic dermatitis, Campaign for Safe Cosmetics: Methylisothiazolinone and Methylchloroisothiazolinone
Monoethanolamine
2-Aminoethanol is a colorless, viscous liquid that, despite not being registered for pesticide use in the U.S, holds vast potential in a variety of applications. It can be used in cutting fluids, production of soaps, surfactants, salts, corrosion control inhibitors, pharmaceuticals, and even in protective topical solutions against chemical warfare agents. Used as a pharmaceutical adjuvant, 2-Aminoethanol is effective as a solvent for fats and oils and in creating emulsion formulas like lotions and creams. However, it poses health risks, as a 5.9% concentration can irritate human skin and inhalation may cause allergic reactions, liver damage, and liver symptoms.
Naphtha
Benzene is a colorless, highly flammable liquid with a sweet smell. It is used in a variety of products, including motor fuels, solvents, pharmaceuticals, and detergents. It's also present in substances such as crude oil, gasoline, and cigarette smoke, and is one of the top 20 most produced chemicals in the U.S. However, benzene is also known to be a human carcinogen, with both acute and chronic exposure causing numerous health concerns, including drowsiness, dizziness, headaches, and irritation in the short-term and blood disorders, reproductive effects, anemia, and an increased risk of leukemia in the long-term. Various measures have been taken to limit benzene exposure, including the U.S. Occupational Safety and Health Administration setting standards for occupational exposure and the European Union reducing the maximum allowed benzene content in gasoline from 5% to 1% by volume in 2000.
Polydimethylsiloxane
Permitted as an inert ingredient in non-food pesticide products, Polydimethylsiloxane is classified as an irritant. According to Scientific Polymer Products MSDS, it may form a siloxane polymer upon contact with skin, eyes, or lungs. This suggests the chemical can potentially cause irritation when users come into direct contact with it during use, emphasizing the importance of protective measures.
Polyoxyethylene
Polyoxyethylene is a potent detergent with capabilities in washing, emulsifying, dispersing, wetting, and solubilizing. When humans consumed polyoxyethylene (20) sorbitan monooleate, it typically showed no toxic effects, but there were isolated allergic reactions. Industrially, this chemical is integral in producing various household cleaning items, including laundry detergents and spot removers, as well as personal care products like creams and lotions.
Sodium Borate
Sodium borate, a toxic white powder, is used in various products ranging from cleaning agents and personal care items to children's toys for pH adjustment. Commonly known as borax, it's found in cleaners, detergents, air fresheners, diaper creams, and some toys like playdough. Although often considered a "green" component, sodium borate can lead to organ system toxicity, fertility issues, harm to an unborn child, endocrine disruption, skin allergies, eye and respiratory irritation, and damage to the male reproductive system. Canada has imposed restrictions on its use in cosmetics.
Sources:
Assessment of consumer exposure to boron in cleaning products: a case study of Canada, Watch Out For Borax, Borax: Not the green alternative it's cracked up to be, Antimicrobial agents, triclosan, chloroxylenol, methylisothiazolinone and borax, used in cleaning had genotoxic and histopathologic effects on rainbow trout ,
Sodium Cumenesulfonate
Sodium Cumenesulfonate is a mild eye irritants that can be significantly absorbed upon ingestion but not after skin application. It has not shown skin sensitization in animal tests but have caused acute toxicity symptoms such as decreased activity, prostration, increased saliva production, diarrhea, and liver congestion. Furthermore, sodium cumenesulfonate has not demonstrated carcinogenic effects in dermal exposure studies.
Sodium Hydroxide
Sodium hydroxide, also known as caustic soda or lye, is an odorless white crystalline solid that absorbs moisture from the air. It generates significant heat when dissolved in water or neutralized with acid which may ignite combustible materials. It is highly corrosive and is typically used as a solid or in a 50% solution. Sodium hydroxide is used to manufacture a variety of products including soaps, rayon, paper, explosives, dyestuffs, and petroleum products. Exposure to this substance may cause severe burns, necrosis, and pulmonary edema, depending on the concentration and exposure method.
Sodium Metasilicate
Sodium metasilicate is a type of compound that includes varying amounts of sodium oxide (Na2-O) and silica (Si2-O), and its aqueous solutions are heavily alkaline and corrosive, typically containing weight ratios of silica to sodium oxide between 1.6 to 3.8. It is a strong irritant for skin and eyes and can be toxic if ingested in high doses. In its aerosol form, it can irritate the skin, eyes, and respiratory tract. The compound, tested at specific molar ratios, has shown corrosive effects on rabbit skin but hasn't shown any sensitizing effects in a local lymph node assay study on mice. Both hydrous and anhydrous forms, including Sodium metasilicate pentahydrate, Sodium metasilicate nonahydrate, Sodium silicate, and Potassium silicate, share similar uses and adverse effects, mainly due to their corrosive effects on metal and tissue resulting from their alkalinity.
Sodium Triphosphate
Sodium triphosphate is identified as a moderate irritant to the skin and mucous membranes. It can manifest as a mild skin, eye, and respiratory tract irritant, particularly in aerosol form. It may cause discomfort in the eyes, nose, and throat. High-dose ingestion in animal studies has also indicated potential for kidney damage. Various sources, including Merck Index, ICSC, CAMEO, CHEMINFO, and MSDSonline indicate its potential as an irritant.
Sulfuric Acid
Sulfuric acid, a clear and highly corrosive liquid, is employed in the creation of fertilizers, other acids, and glue, and is used in petroleum purification, metal pickling, and lead-acid batteries. It can cause severe burns, is a potential human carcinogen, can trigger pulmonary edema, and may erode tooth enamel.
Triethanolamine
Triethanolamine appears to cause occupational asthma and allergic contact dermatitis in machinists and photographers, as well as liver and kidney damage in animals with high-dose feeding. It's noted to be an irritant to the skin, eyes, and respiratory tract, with potential to cause skin sensitization, though the rate of skin sensitization in humans is low. Triethanolamine has low acute toxicity, with median oral LD50 values of 4,190-11,260 mg/kg in rats and 5,300-8,000 mg/kg in guinea pigs, and a median dermal LD50 greater than 2,000 mg/kg in rabbits. Triethanolamine is not carcinogenic, developmental toxicant, or toxic to the reproductive system. However, chronic exposure may lead to liver and kidney damage.
Sources:
Safety assessment of triethanolamine and triethanolamine-containing ingredients as used in cosmetics, Toxicology of mono-, di-, and triethanolamine, Campaign for Safe Cosmetics: Ethanolamine Compounds (MEA, DEA, TEA And Others), The Dirty Dozen: DEA-related ingredients, Chemical Profile, Special Chem, Safety assessment of triethanolamine and triethanolamine-containing ingredients as used in cosmetics
Potassium Hydroxide
Potassium hydroxide 30-70% is a liquid that is highly corrosive to skin, causing second or third-degree burns even after brief contact. It is a hazardous substance that can also induce pulmonary edema, a condition characterized by excessive fluid in the lungs. The effects and properties of this chemical can be compared to those of Sodium hydroxide.
1,4-Dioxane
1,4-Dioxane is a clear, water-soluble liquid that is primarily used as a solvent in chemical manufacturing and laboratory reagents. Other uses leverage its solvent properties, including cosmetics, detergents, and shampoos. However, manufacturers generally reduce 1,4-Dioxane to low levels in these products due to its potential health risks. Acute exposure can result in symptoms such as vertigo, drowsiness, and irritation of the eyes, nose, throat, and skin. Chronic exposure may lead to liver and kidney damage, and the substance is classified as a probable human carcinogen by the EPA. Notably, severe kidney and liver damage, CNS effects, and even death have been recorded after heavy or prolonged exposure.
Sources:
What Is 1,4-Dioxane in Laundry and Cleaning Products?, Effect of ethoxylation and lauryl alcohol on the self-assembly of sodium laurylsulfate: Significant structural and rheological transformation, Final Risk Evaluation for 1,4-Dioxane, Ongoing and Completed Chemical Risk Evaluations under TSCA, Preliminary Information on Manufacturing, Processing, Distribution, Use, and Disposal, TOXICOLOGICAL REVIEW OF 1,4-DIOXANE, 15th Report on Carcinogens, 1,4-Dioxane, Determination of residual 1,4-dioxane in surfactants and cleaning agents using headspace single-drop microextraction followed by gas chromatography–flame ionization detection, 1,4-Dioxane in Cosmetics: A Manufacturing Byproduct, An integrated assessment of the 1,4-dioxane cancer mode of action and threshold response in rodents, Campaign for Safe Cosmetics: 1,4-DIOXANE, Product Profile: Hand Sanitizer, Occurrence of 1,4-dioxane in cosmetic raw materials and finished cosmetic products, Chemical Profile: 1,4-dioxane
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