Best Non-Toxic Dish Soap in 2024
As an Amazon Associate, we earn from qualifying purchases. Our use of affiliate links does not influence how we rate products. Learn more about our affiliate policy here.
What you should know when choosing non-toxic dish soap on Welpr:
- Only the cleanest products make it onto Welpr.
- We use a score called the Welpr Rating to rank each product.
- The Welpr Rating is based on math, not opinion, ensuring it's free from human bias.
Find Non-Toxic Dish Soap
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Pure Castile Soap, Peppermint - Dr. Bronner's
Product Details
- Made with over 70% certified organic and fair trade ingredients, promoting ethical working conditions and fair pricing.
- Contains organic and fair trade palm kernel oil sourced from smallholder farmers in Ecuador, supporting sustainable practices and local habitats.
- Free from synthetic preservatives, detergents, or foaming agents, ensuring suitability for environmentally conscious users.
- Highly concentrated, offering versatile usage including laundry, mopping, and dishwashing, reducing waste in packaging.
- Packaging uses 100% post-consumer recycled plastic bottles, minimizing environmental impact by diverting plastic from landfills.
- Product certifications include USDA Certified Organic, Fair For Life, Certified Vegan, Certified Leaping Bunny, and B Corp.
- Supports regenerative organic farming practices, increasing biodiversity and combating climate change.
- Commits to fair trade, ensuring fair wages and conditions for farmers and suppliers.
- Company caps executive salaries at 5 times that of the lowest-paid full-time employees to share profits equitably.
- Soap production powered by renewable energy and practices aiming to remove greenhouse gases from the environment.
Pros & Cons
Pros Mentioned
- Refreshing
- Versatile
- Cleansing
Cons Mentioned
- Drying
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, Organic Coconut Oil, Potassium Hydroxide, Organic Palm Kernel Oil, Organic Olive Oil, Mentha Arvensis, Organic Hemp Oil, Organic Jojoba Oil, Mentha Piperita, Citric Acid, Tocopherol, Ingredients Vary By Scent
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Sal Suds Biodegradable Cleaner, Pine - Dr. Bronner's
Product Details
- Versatile all-purpose cleaner suitable for cleaning floors, laundry, dishes, furniture, and cars, without irritating skin.
- Effective in both hard and soft water, rinses freely in hot or cold water and rapidly biodegrades.
- Formulated with plant-based surfactants that cut grease and dirt, producing copious suds.
- Mildly scented with pure fir and spruce essential oils, free from synthetic dyes, fragrances, or preservatives, phthalates, and ammonium compounds.
- Product ingredients are never tested on animals and bear the Leaping Bunny logo for cruelty-free certification.
- Contains the purest organic and fair trade ingredients, promoting regenerative organic farming practices to enrich soil and increase biodiversity.
- Certifications include USDA Certified Organic, Fair For Life, Certified Vegan, Certified Leaping Bunny, and B Corp, ensuring ethical standards and environmental responsibility.
- Supports various causes like regenerative agriculture, fair trade, wage equality, and animal welfare.
- Emphasizes sustainability with a commitment to using renewable energy and post-consumer recycled plastic in product packaging.
Pros & Cons
Pros Mentioned
- Versatile
- Concentrated
- Effective
Cons Mentioned
- Pricey
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, Sodium Lauryl Sulfate, Coco-Betaine, Decyl Glucoside, Abies Siberica (Siberian Fir) Needle Oil, Picea Glauca (Spruce) Leaf Oil, Citric Acid, Sodium Sulfate, Sodium Chloride, Potassium Hydroxide
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Nature+ Dishwashing Liquid, Unscented - Attitude
Product Details
- EWG Verified for clean ingredients and full transparency.
- Made with ≥ 97% naturally sourced ingredients.
- Formulated with plant-based and mineral ingredients to clean and eliminate dirt.
- Packaging is easily recyclable, made from HDPE #2 plastic.
- 100% vegan and cruelty-free certified by PETA.
- Strong degreasing power with foaming action eliminates grease and residue.
- Ideal for people sensitive to fragrances.
- Leaves dishes clean and sparkling.
Pros & Cons
Pros Mentioned
- Effective
- Natural
- Non-toxic
Cons Mentioned
- Pricey
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: <5% Anionic Surfactants (Sodium Coco-Sulfate), <5% Non-Ionic Surfactants (Lauryl Glucoside), Contains Also: Water, Glycerin, Sodium Benzoate, Sodium Gluconate, Potassium Sorbate, Camellia Sinensis (Green Tea/Thé Vert) Leaf Extract, Sodium Chloride, Triethyl Citrate, Terpineol Acetate, Terpineol, Tetrahydrolinalool, Fragrance
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Dishmate Dish Soap, Unscented - ECOS
Pros & Cons
Pros Mentioned
- Healthy
- Value
- Effective
Cons Mentioned
- Pricey
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, Sodium Coco Sulfate, Cocamidopropylamine Oxide, Lauramine Oxide, Coco Betaine, Phenoxyethanol, Ethylhexyl-Glycerin, Tetrasodium Glutamate Diacetate, Citric Acid
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Liquid Dish Soap, Lemon - 9 Elements
Pros & Cons
Pros Mentioned
- Effective
- Natural
- Fresh
Cons Mentioned
- Messy
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, Lauryl Glucoside, Sodium Citrate, C10-16 Alkyldimethylamine Oxide, Glycerin, Essential Oil, Sodium Acetate, Citric Acid, Vinegar
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Dish Soap Bar, Unscented - Meliora Cleaning Products
Product Details
- Easy to use: Effectively removes food stains, oils, and grime from various dishware and cookware.
- Concentrated formula: Designed to minimize waste and environmental impact, eliminates the need for plastic and preservatives.
- Plastic-free packaging: Comes in recyclable and compostable paperboard box, without single-use plastics or hidden liners.
- Safe ingredients: Contains organic coconut and sunflower oil-based soaps; ingredients are fully disclosed on the product label.
- Eco-friendly certifications: MADE SAFE certified, Leaping Bunny certified, vegan, and made by a B Corp Certified woman-owned small business in the USA.
- Supports environmental causes: Donates 2% of annual revenue to environmental organizations.
- Planet-friendly packaging: Uses vegetable-based inks for printing on the paperboard boxes.
- Non-toxic and cruelty-free: Free from synthetic fragrances, preservatives, dyes, and palm oil.
- Additional ingredients benefits: Includes sodium cocoate and sodium sunflowerate for effective cleaning, and maintains excess oils for a moisturizing feel.
- Glycerin: Naturally created during soapmaking, known for skin-softening and effective cleaning properties.
- Available in unscented or lemon-scented versions using organic lemon essential oil.
Pros & Cons
Pros Mentioned
- Biodegradable
- Lathers
- Non-toxic
Cons Mentioned
- Filmy
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Sodium Cocoate (Vegetable Soap), Sodium Sunflowerate (Vegetable Soap), Cocos Nucifera Oil (Organic Coconut Oil), Helianthus Annuus Oil (Organic Sunflower Oil), Glycerin
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Dish Soap, Unscented - Better Life
Pros & Cons
Pros Mentioned
- Natural
- Effective
- Gentle
Cons Mentioned
- Expensive
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Purified Water, Potassium Cocoate (Natural Castile Soap), Lauryl Glucoside (Plant Derived), Caprylyl/Capryl Glucoside (Plant Derived), Decyl Glucoside (Plant Derived), Glycerin (Vegetable), Disodium Coco-Glucoside Citrate, Aloe Barbadensis Leaf Extract, Tocopherol (Vitamin E)
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
High Performing Dish Soap, Linen - L'Avant Collective
Product Details
- Features a plant-based, high-performing formula designed to effectively cut through grease while being gentle on skin.
- Comes in a matte white reusable glass bottle, promoting environmental sustainability by design to be reused.
- Leverages a cruelty-free formulation, certified by Leaping Bunny, ensuring it is not tested on animals.
- Offers a fresh linen scent, enhancing the dishwashing experience with a pleasant fragrance.
Pros & Cons
Pros Mentioned
- Pretty
- Long-lasting
- Aesthetically
Cons Mentioned
- Damaged
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Water, Sodium Coco-Sulfate, Aloe Barbadensis Leaf Juice, Glycerin, Lauramine Oxide, Alkyl Polyglucoside, Natural Fragrance, Alkanoate Salt, Magnesium Chloride, Citric Acid, Phenoxyethanol, Ethylhexylglycerin, Ocimum Basilicum (Basil) Oil, Citrus Limon (Lemon) Peel Oil, Lavandula Angustifolia (Lavender) Oil, Pelargonium Graveolens (Geranium) Oil, Salvia Sclarea (Clary Sage) Oil
Third-party certifications are key indicators of a product's safety, ethics, and environmental impact. Click the icon to verify the certification.
Highlights aren't always verifiable, so you're trusting the brand when they say "lead free", etc. If the highlight icon is "clickable", it means we've verified the highlight.
User satisfaction is calculated using online reviews and a Bayesian average across all cleaning products on Welpr.
Super Deluxe Dish Soap, Peppermint & Lemon - Rebel Green
Product Details
- Kissed with pure essential oils for an effective dish wash that cleans both hands and dishes.
- Made with earth-friendly ingredients formulated without synthetic fragrances, sulfates, or other harsh materials.
- Safe for all skin types, including sensitive skin and allergies, combining gentle ingredients and essential oils.
- Environmentally conscious packaging made with fully recyclable materials.
- Part of a natural cleaning product line designed to promote a healthier lifestyle.
Pros & Cons
Pros Mentioned
- Refreshing
- Moisturizing
- Eco-friendly
Cons Mentioned
- Inefficient
Ingredients
Ingredients can vary by product variation and may change at any time by the manufacturer. For the most complete and up-to-date list of ingredients, refer to the product packaging.
To analyze individual ingredients, use this EWG tool.
Ingredients: Aqua (Water), Capryloyl/-caproyl, Methyl Glucamide, Propylene Glycol, Lauryl Glucoside, Sodium Lauroyl Sarcosinate, Disodium Cocoamphodiacetate, Sodium Lauroyl Lactylate (Plant Derived Surfactants), Phenoxyethanol (Preservative), 2-Hydroxypropyl Ether (Guar Gum) (Thickener), Mentha Piperitas And Citrus Limon Peel Oil (Fragrance)
Common Harmful Chemicals in Dish Soap
Chemical Name
Why it’s harmful
Sodium triphosphate is identified as a moderate irritant to the skin and mucous membranes. It can manifest as a mild skin, eye, and respiratory tract irritant, particularly in aerosol form. It may cause discomfort in the eyes, nose, and throat. High-dose ingestion in animal studies has also indicated potential for kidney damage. Various sources, including Merck Index, ICSC, CAMEO, CHEMINFO, and MSDSonline indicate its potential as an irritant.
Triclosan is a synthetic pesticide with antibacterial properties commonly added to detergents, soaps, and various personal care products such as deodorants and toothpastes. Although it lacks the ability to combat viruses causing colds and flus, it's used in products like body washes, disinfectants, and some toothpastes to resist bacterial growth. In 2016, the FDA limited its use in antibacterial soaps, but the compound is still permitted in other products. The European Union prohibited its presence in food-contact items in 2010. Exposure to triclosan has been associated with hormone disruption, increased breast cancer risk, liver damage, and the development of resistant super-germs.
Triclosan Exposure, Transformation, and Human Health Effects, Are antibacterial products with triclosan fueling bacterial resistance?, Antimicrobial agents, triclosan, chloroxylenol, methylisothiazolinone and borax, used in cleaning had genotoxic and histopathologic effects on rainbow trout, The Effects of Triclosan on Puberty and Thyroid Hormones in Male Wistar Rats, Triclosan is a potent inhibitor of estradiol and estrone sulfonation in sheep placenta, The in Vitro estrogenic activities of triclosan and triclocarban, Antibacterial Soap? You Can Skip It, Use Plain Soap and Water, Environmental Exposure of Aquatic and Terrestrial Biota to Triclosan and Triclocarban, Triclosan: Environmental Fate and Effects, Chemical Profile: Triclosan / Triclocarban, 5 Things to Know About Triclosan, Underarm Harm? Whats So Bad About Antiperspirants?, Some flame retardants and the antimicrobials triclosan and triclocarban enhance the androgenic activity in vitro, Triclocarban Enhances Testosterone Action: A New Type of Endocrine Disruptor?, Triclosan, a commonly used bactericide found in human milk and in the aquatic environment in Sweden
Sodium Dichloroisocyanurate is toxic upon ingestion and act as a strong oxidizer, posing a fire hazard when exposed to organic materials. It may react violently with combustible substances and decompose due to heat or water, releasing toxic gases such as chlorine. It can cause irritation to the skin, eyes and respiratory tract, and prolonged exposure can result in corrosive skin burns. Inhalation of high concentrations can lead to acute pulmonary edema. It may also explode from shock, friction, or other ignition sources, and can cause fires upon contact with combustible materials.
Diethanolamine is a chemical found in various consumer products like shampoos, cosmetics, and pharmaceuticals. Acute exposure in humans can result in irritation of the nose, throat, and skin. However, no detailed data is available on its chronic, reproductive, developmental or carcinogenic effects on humans. Studies on animals reveal that acute oral exposure can influence the liver, blood, kidney, and central nervous system, while dermal exposure has been connected with an increased incidence of liver and kidney tumors in mice. Production of first-degree burns, skin irritation, occupational asthma, kidney, and liver injury risk, and potential skin sensitization are some other adverse effects associated with diethanolamine.
Chemical Safety Facts: Ethanolamines, NTP Toxicology and Carcinogenesis Studies of Diethanolamine, California Environmental Protection Agency: Diethanolamine , International Agency for Research on Cancer: Diethanolamine, Initial List of Hazardous Air Pollutants with Modifications, What is the Toxics Release Inventory?, OPINION CONCERNING DIALKYL- AND DIALKANOLAMINES AND THEIR SALTS IN COSMETIC PRODUCTS, Ethanolamine Compounds (MEA, DEA, TEA And Others), WHAT ARE ETHANOLAMINE COMPOUNDS (DEA, MEA, OR TEA): CHEMICAL FREE LIVING, The Dirty Dozen: DEA-related ingredients, FDA: Diethanolamine, Chemical Profile: Diethanolamine ,
2-Aminoethanol is a colorless, viscous liquid that, despite not being registered for pesticide use in the U.S, holds vast potential in a variety of applications. It can be used in cutting fluids, production of soaps, surfactants, salts, corrosion control inhibitors, pharmaceuticals, and even in protective topical solutions against chemical warfare agents. Used as a pharmaceutical adjuvant, 2-Aminoethanol is effective as a solvent for fats and oils and in creating emulsion formulas like lotions and creams. However, it poses health risks, as a 5.9% concentration can irritate human skin and inhalation may cause allergic reactions, liver damage, and liver symptoms.
Formaldehyde is a colorless, flammable gas with a pungent smell that's naturally produced in small quantities in human bodies and is also known as methanal amongst other names. It's used in the production of various items such as fertilizers, paper, plywood, and urea-formaldehyde resins as well as in some foods and household products like antiseptics, medicines, and cosmetics. Exposure to formaldehyde, which can occur through breathing contaminated indoor air, tobacco smoke, or ambient urban air can lead to respiratory symptoms, irritation of the eyes, nose and throat and has been linked to lung and nasopharyngeal cancer as well as leukemia. The EPA considers formaldehyde a probable human carcinogen (Group B1) and inhaling it can cause bronchospasm and pulmonary edema. Commercially, it's sold as formalin in solutions of 37%, 44%, or 50% and long-term exposure can cause first-degree burns, skin sensitization, squamous cell nasal cancer, and chronic pulmonary obstruction.
Formaldehyde and Cancer Risk, Cleaning Products & Indoor Air Quality, No More Toxic Tub, Campaign for Safe Cosmetics: Preservatives, Campaign for Safe Cosmetics: Formaldehyde And Formaldehyde-Releasing Preservatives, Formaldehyde may be found in cosmetic products even when unlabelled, Formaldehyde Found in Popular American Beauty Products, Hair Salons - Formaldehyde in Your Products, Formaldehyde in cosmetic products
Sodium laureth sulfate, derived from ethoxylated lauryl alcohol, is a surfactant used in sudsy products like toothpaste, detergents, and shampoos. While it acts as a cleansing and emulsifying agent, it can sometimes contain toxic impurities such as 1,4-dioxane. This chemical has raised health concerns due to its potential to cause skin, lung, and eye irritation, organ toxicity, and, primarily because of contamination by 1,4 dioxane, cancer.
The Dirty Dozen: Sodium Laureth Sulfate, 15 Toxic Trespassers, SKIP PRODUCTS MADE WITH SLES (AND SLS, TOO!), Campaign for Safe Costmetics: 1,4-DIOXANE, WHAT IS SODIUM LAURETH SULFATE: CHEMICAL FREE LIVING, A new formula for a mild body cleanser: sodium laureth sulphate supplemented with sodium laureth carboxylate and lauryl glucoside,
Sodium Lauryl Sulfate is recognised as a skin, eye, and respiratory tract irritant according to ICSC. It may cause allergic reactions and eye irritation as stated by the HSDB. Exposure may even result in eye burns, as per CAMEO. Depending on its form - which may range from a solid (90-98% purity), to a paste (30-41%), or an aqueous solution (28-50%) - it can significantly irritate skin and eyes, with adverse effects escalating with increased concentration. Despite these hazards, it is not a skin sensitizer according to CHEMINFO, while eChemPortal: ERMA and MSDSonline endorse its classification as an irritant.
Triethanolamine appears to cause occupational asthma and allergic contact dermatitis in machinists and photographers, as well as liver and kidney damage in animals with high-dose feeding. It's noted to be an irritant to the skin, eyes, and respiratory tract, with potential to cause skin sensitization, though the rate of skin sensitization in humans is low. Triethanolamine has low acute toxicity, with median oral LD50 values of 4,190-11,260 mg/kg in rats and 5,300-8,000 mg/kg in guinea pigs, and a median dermal LD50 greater than 2,000 mg/kg in rabbits. Triethanolamine is not carcinogenic, developmental toxicant, or toxic to the reproductive system. However, chronic exposure may lead to liver and kidney damage.
Safety assessment of triethanolamine and triethanolamine-containing ingredients as used in cosmetics, Toxicology of mono-, di-, and triethanolamine, Campaign for Safe Cosmetics: Ethanolamine Compounds (MEA, DEA, TEA And Others), The Dirty Dozen: DEA-related ingredients, Chemical Profile, Special Chem, Safety assessment of triethanolamine and triethanolamine-containing ingredients as used in cosmetics
Ammonium hydroxide is a corrosive substance that can cause injury to the skin, eyes, and respiratory tract. High concentrations, either through inhalation or prolonged exposure, can lead to significant respiratory issues, including inflammation, pneumonia, and pulmonary edema. It is used in various industries such as fertilizers, dyes, explosives, plastics, and cleansing agents, among others. Due to its intense pungency and potential to cause extreme irritation and even life-threatening conditions, precautions such as wearing protective clothing and immediate cleansing of affected areas are recommended. It should be stored away from combustibles and heavy metals, in well-ventilated areas and in specified containers. Disposal guidelines also need to be referred from environmental regulatory agencies due to the hazardous nature of the substance.
The Facts About Ammonia, Chemical Safety Facts: Ammonia, ATSDR Chemical Profile, EPA: Ammonia, Aquatic Life Ambient Water Quality Criteria for Ammonia - Freshwater, EPA Chemical Profile, Mass Casualties from Acute Inhalation of Chloramine Gas, Ventilatory disorders associated with occupational inhalation exposure to ammonia, Ecological and toxicological effects of inorganic nitrogen pollution in aquatic ecosystems: A global assessment, TOXICOLOGICAL PROFILE FOR AMMONIA ,
Volatile organic compounds (VOCs) are released by many cleaning products, as revealed by a study in Chemosphere which analyzed 30 such items. Of the 530 distinct VOCs identified, 193 were considered hazardous, linked to health issues like respiratory system damage and cancer. Indoor air contamination from VOCs is significantly higher than outdoor, with up to 10 times more pollutants. However, products labeled as green, particularly those without fragrances, exhibited fewer hazardous VOC emissions. Exposure to VOCs has critical health implications, especially for cleaning industry workers and children, and these compounds also contribute to outdoor air pollution.
Chloroxylenol is a widely used disinfectant in homes and hospitals. It is also used as a preservative in liquid soaps. However, there are reports of individuals, specifically housekeepers, developing allergic contact dermatitis as a result of exposure to this chemical.
Testicular Toxicity of Chloroxylenol in Rats: Biochemical, Pathological and Flow Cytometric Study, Human health risk assessment of chloroxylenol in liquid hand soap and dishwashing soap used by consumers and health-care professionals, Chemical Profile: Chloroxylenol, Antimicrobial agents, triclosan, chloroxylenol, methylisothiazolinone and borax, used in cleaning had genotoxic and histopathologic effects on rainbow trout, Removal of Chloroxylenol Disinfectant by an Activated Sludge Microbial Community, Chloroxylenol at environmental concentrations can promote conjugative transfer of antibiotic resistance genes by multiple mechanisms, Impact of benzalkonium chloride, benzethonium chloride and chloroxylenol on bacterial antimicrobial resistance, Human exposure and health risk assessment of an increasingly used antibacterial alternative in personal care products: Chloroxylenol, RED FACTS: Chloroxylenol
Butoxyethanol studies show severe effects in mice including hemoglobinuria and changes to the lungs, kidneys, and liver. Human volunteers exposed to 200 ppm for 8 hours showed no adverse effects except for mucous membrane irritation. There is, however, limited evidence of spontaneous abortions and decreased sperm counts in humans, and more conclusive evidence of birth defects and testicular damage in animals. Humans are resistant to butoxyethanol-induced red blood cell hemolysis.
Benzyl alcohol can occasionally lead to allergic contact dermatitis or occupational contact urticaria. It can irritate the skin and eyes, and inhalation at high quantities can result in central nervous system effects. Rats exposed to high concentrations showed no deaths, however, it has caused fatalities in premature infants when given in IV solutions at doses over 4.5mg/kg a day. The substance is quickly metabolized to hippuric acid and is noted as a known contact allergen in humans.
Isothiazolinones are preservatives known to cause allergic contact dermatitis, primarily in workers involved in manufacturing industries like paint, paper, rubber, and air fresheners. Additionally, there's a reported case of occupational asthma from exposure to this chemical among workers.
DMDM hydantoin is a substance used in cosmetics that has the potential to cause allergic contact dermatitis, although rinse-off products generally have a low risk. According to various reports, skin sensitization patch testing has yielded positive results.
Ethyl acetate is a volatile substance, recognized by the U.N. International Drug Control Programme for its potential to cause narcosis when inhaled. It is also listed as an irritant to the eyes and respiratory tract. Furthermore, when subjected to high concentrations, ethyl acetate can cause adverse effects on the Central Nervous System (CNS).
Butylphenyl methylpropional, also known as lilial, is a chemical compound commonly used in cosmetics and laundry powders. It is found naturally in crow-dipper and tomato plants and is also produced synthetically in large quantities. In May 2019, the EU's Scientific Committee on Consumer Safety (SCCS) deemed its use in cosmetics as unsafe. Following animal studies indicating reproductive toxicity, the EU banned its use in cosmetics by March 2022. Moreover, butylphenyl methylpropional can sometimes serve as an allergen, potentially leading to contact dermatitis in susceptible individuals.
Fragranced consumer products: exposures and effects from emissions, 10 reasons to avoid synthetic fragrances in cleaning products, Synthetic chemical in consumer products linked to early death, study finds, Review of the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens, Expert Panel Confirms that Fragrance Ingredient Can Cause Cancer, Fragrances, Beyond the Label: Health Impacts of Harmful Ingredients in Cleaning Products
Laureth-7, a surfactant derived from lauryl alcohol sourced from coconut or palm oil, is commonly used in personal care and household products, especially laundry detergents. In detergents, it functions by reducing surface tension between water and soil, aiding in the removal of dirt, stains, and oils from fabrics. This ingredient belongs to the Polyethylene Glycols (PEGs) family, which is found in various consumer goods. Despite past contamination concerns, modern manufacturing processes have addressed and eliminated these issues. Although PEGs are not used in certain personal care products, their inclusion in machine detergents is deemed acceptable since they don't directly touch the skin.
d-Limonene is a liquid with a lemon-like smell, often used as a solvent to substitute for more volatile and toxic organic solvents. When it comes into contact with air, it can oxidize, and this oxidized form is a known skin sensitizer, capable of irritating skin and eyes. The combination of d-limonene and l-limonene is known as limonene or dipentene. The estimated lethal dose for humans is between 0.5 to 5 g/kg, and studies have shown that it can cause diarrhea and liver effects when ingested in high doses.
Linalool is a naturally occurring terpene alcohol found in many flowers and spice plants, consisting of two enantiomers. It is widely used in commercial products for its pleasant floral and spicy scent, serving as a key ingredient in soaps, fragrances, food flavors, household products, and insecticides. In plants, linalool functions as a metabolite, volatile oil component, antimicrobial agent, and aroma compound. Acute exposure to linalool can lead to central depressive effects with symptoms such as ataxia, reduced motor activity, and respiratory disturbances. Additionally, inhalation, oral intake, or skin absorption can result in irritation, pain, and allergic reactions.
5-chloro-2-methyl-4-isothiazolin-3-one (CMI) is a compound frequently used as a preservative in cosmetics, hygiene products, and other industrial applications such as hydraulic fracturing fluids. It can also be deployed as a pesticide in the U.S, pending regulatory approval. CMI, which is often used in combination with 2-methyl-4-isothiazolin-3-one (MI), can cause contact dermatitis in humans. Various animal studies have shown that a high exposure to a CMIT/MIT mixture can cause alterations in rats' liver function. The production and use of CMI in a range of products mean it can be release into the environment, with some susceptibility to degradation through photolysis in sunlight. Its mobility in soil is high but volatilization from soil or water surfaces is not expected to be significant. Occupational and general exposure to CMI can occur especially through inhalation and dermal contact with CMI-containing products.
Antimicrobial agents, triclosan, chloroxylenol, methylisothiazolinone and borax, used in cleaning had genotoxic and histopathologic effects on rainbow trout, Methylisothiazolinone toxicity and inhibition of wound healing and regeneration in planaria, Methylchloroisothiazolinone and/or methylisothiazolinone in cosmetic products, Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles, Methylisothiazolinone and isothiazolinone allergy, Analysis of isothiazolinones in environmental waters by gas chromatography–mass spectrometry, Methylisothiazolinone induces apoptotic cell death via matrix metalloproteinase activation in human bronchial epithelial cells, EU REGULATIONS , Methylisothiazolinone contact allergy: a review, Effects of methylisothiazolinone and octylisothiazolinone on development and thyroid endocrine system in zebrafish larvae, Two Cases of Chloromethylisothiazolinone and Methylisothiazolinone-associated Toxic Lung Injury, An update of the risk assessment for methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) with focus on rinse-off products, Effects of a mixture of chloromethylisothiazolinone and methylisothiazolinone on peripheral airway dysfunction in children, Isothiazolinone preservative: cause of a continuing epidemic of cosmetic dermatitis, Campaign for Safe Cosmetics: Methylisothiazolinone and Methylchloroisothiazolinone
Methylisothiazolinone can reportedly cause allergic contact dermatitis in workers who interact with products containing it. This substance is recognized as a contact allergen for consumers using cosmetics that include it. It can cause skin burns and sensitization, and inhaling it may lead to corrosive injuries in the upper respiratory tract and lungs. Ingesting this substance is harmful, and inhalation is toxic. This preservative is linked to the category of isothiazolinones.
Antimicrobial agents, triclosan, chloroxylenol, methylisothiazolinone and borax, used in cleaning had genotoxic and histopathologic effects on rainbow trout, Methylisothiazolinone toxicity and inhibition of wound healing and regeneration in planaria, Methylchloroisothiazolinone and/or methylisothiazolinone in cosmetic products, Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles, Methylisothiazolinone and isothiazolinone allergy, Analysis of isothiazolinones in environmental waters by gas chromatography–mass spectrometry, Methylisothiazolinone induces apoptotic cell death via matrix metalloproteinase activation in human bronchial epithelial cells, EU REGULATIONS , Methylisothiazolinone contact allergy: a review, Effects of methylisothiazolinone and octylisothiazolinone on development and thyroid endocrine system in zebrafish larvae, Two Cases of Chloromethylisothiazolinone and Methylisothiazolinone-associated Toxic Lung Injury, An update of the risk assessment for methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) with focus on rinse-off products, Effects of a mixture of chloromethylisothiazolinone and methylisothiazolinone on peripheral airway dysfunction in children, Isothiazolinone preservative: cause of a continuing epidemic of cosmetic dermatitis, Campaign for Safe Cosmetics: Methylisothiazolinone and Methylchloroisothiazolinone
Sodium hydroxide, also known as caustic soda or lye, is an odorless white crystalline solid that absorbs moisture from the air. It generates significant heat when dissolved in water or neutralized with acid which may ignite combustible materials. It is highly corrosive and is typically used as a solid or in a 50% solution. Sodium hydroxide is used to manufacture a variety of products including soaps, rayon, paper, explosives, dyestuffs, and petroleum products. Exposure to this substance may cause severe burns, necrosis, and pulmonary edema, depending on the concentration and exposure method.
Sulfuric acid, a clear and highly corrosive liquid, is employed in the creation of fertilizers, other acids, and glue, and is used in petroleum purification, metal pickling, and lead-acid batteries. It can cause severe burns, is a potential human carcinogen, can trigger pulmonary edema, and may erode tooth enamel.
Isopropyl alcohol has been shown to cause narcosis in animals during acute studies, as cited by ACGIH. However, according to research by Zimmerman, it is not hepatotoxic in either experimental animal studies or in human exposures. It's known to be a skin, eye, and respiratory tract irritant, and if inhaled in high concentrations, it can cause CNS depression, as indicated by the ICSC.
Potassium hydroxide 30-70% is a liquid that is highly corrosive to skin, causing second or third-degree burns even after brief contact. It is a hazardous substance that can also induce pulmonary edema, a condition characterized by excessive fluid in the lungs. The effects and properties of this chemical can be compared to those of Sodium hydroxide.
1,4-Dioxane is a clear, water-soluble liquid that is primarily used as a solvent in chemical manufacturing and laboratory reagents. Other uses leverage its solvent properties, including cosmetics, detergents, and shampoos. However, manufacturers generally reduce 1,4-Dioxane to low levels in these products due to its potential health risks. Acute exposure can result in symptoms such as vertigo, drowsiness, and irritation of the eyes, nose, throat, and skin. Chronic exposure may lead to liver and kidney damage, and the substance is classified as a probable human carcinogen by the EPA. Notably, severe kidney and liver damage, CNS effects, and even death have been recorded after heavy or prolonged exposure.
What Is 1,4-Dioxane in Laundry and Cleaning Products?, Effect of ethoxylation and lauryl alcohol on the self-assembly of sodium laurylsulfate: Significant structural and rheological transformation, Final Risk Evaluation for 1,4-Dioxane, Ongoing and Completed Chemical Risk Evaluations under TSCA, Preliminary Information on Manufacturing, Processing, Distribution, Use, and Disposal, TOXICOLOGICAL REVIEW OF 1,4-DIOXANE, 15th Report on Carcinogens, 1,4-Dioxane, Determination of residual 1,4-dioxane in surfactants and cleaning agents using headspace single-drop microextraction followed by gas chromatography–flame ionization detection, 1,4-Dioxane in Cosmetics: A Manufacturing Byproduct, An integrated assessment of the 1,4-dioxane cancer mode of action and threshold response in rodents, Campaign for Safe Cosmetics: 1,4-DIOXANE, Product Profile: Hand Sanitizer, Occurrence of 1,4-dioxane in cosmetic raw materials and finished cosmetic products, Chemical Profile: 1,4-dioxane